Paper
Palladium-catalyzed carbonylative cyclization of β-bromo-α,β-unsaturated carboxylic acids with 2,2-dimethylhydrazine leading to 1-(dimethylamino)-1H-pyrrole-2,5-diones
Published Apr 1, 2014 · Yeon Kyu Bae, C. Cho
Applied Organometallic Chemistry
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Abstract
β-Bromo-α,β-unsaturated carboxylic acids are carbonylatively cyclized with 2,2-dimethylhydrazine under carbon monoxide pressure in THF in the presence of a catalytic amount of a palladium catalyst along with a base to give 1-(dimethylamino)-1H-pyrrole-2,5-diones. Copyright © 2014 John Wiley & Sons, Ltd.
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Palladium-catalyzed carbonylative cyclization of -bromo-,-unsaturated carboxylic acids with 2,2-dimethylhydrazine leads to 1-(dimethylamino)-1H-pyrrole-2,5-dione
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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