Paper
Papillary Adenocarcinoma of the Lung. Case Report of Uncommon Tumor and Review of the Literature
Published 2021 · Kirk A Sheplay, J. Nicholas, A. Lombard
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Abstract
Based on the new 2015 WHO classification of lung tumors, invasive adenocarcinomas with multiple different patterns should no longer be classified as “mixed adenocarcinoma”, and each subtype must be assessed and reported semi-quantitatively (in 5% increments). Papillary adenocarcinoma (PA) is a subtype of invasive adenocarcinoma defined by presence of papillary structures with true fibrovascular cores replacing the alveolar lining or present within the alveolar spaces. Pure lung papillary adenocarcinoma represents about 7.4-12% of lung adenocarcinomas. We report a case of papillary lung adenocarcinoma presenting as a small solitary nodule, and we discuss diagnostic features, differential diagnosis, molecular changes, treatment, and prognosis.
Papillary lung adenocarcinoma is a rare and potentially malignant tumor with a small solitary nodule presenting as a small solitary nodule.
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