Paper

Paroxetine and rivastigmine mitigates adjuvant‐induced rheumatoid arthritis in rats: Impact on oxidative stress, apoptosis and RANKL/OPG signals

Published Nov 1, 2018 · Sara I. Shafiey, Wafaa R. Mohamed, Ali A Abo-Saif

Life Sciences

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Abstract

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RCTAnimal Study

Study Snapshot

Paroxetine and rivastigmine show antirheumatoid effects in CFA-induced rheumatoid arthritis in rats, mediated through antioxidant, anti-inflammatory, antiapoptotic, and modulation of RANKL/OPG expression levels.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paroxetine and rivastigmine mitigates adjuvant‐induced rheumatoid arthritis in rats: Impact on oxidative stress, apoptosis and RANKL/OPG signals

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