Paper
Pathogenesis of the Pseudomonas aeruginosa Biofilm: A Review
Published Feb 27, 2022 · F. Tuon, Leticia Ramos Dantas, P. Suss
Pathogens
221
Citations
4
Influential Citations
Abstract
Pseudomonas aeruginosa is associated with several human infections, mainly related to healthcare services. In the hospital, it is associated with resistance to several antibiotics, which poses a great challenge to therapy. However, one of the biggest challenges in treating P. aeruginosa infections is that related to biofilms. The complex structure of the P. aeruginosa biofilm contributes an additional factor to the pathogenicity of this microorganism, leading to therapeutic failure, in addition to escape from the immune system, and generating chronic infections that are difficult to eradicate. In this review, we address several molecular aspects of the pathogenicity of P. aeruginosa biofilms.
The complex structure of Pseudomonas aeruginosa biofilms contributes to its pathogenicity, leading to therapeutic failure, immune system escape, and difficult-to-eradicate chronic infections.
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