How perchlorate improves excitation-contraction coupling in skeletal muscle fibers.

doi:10.1016/S0006-3495(83)84346-X

Paper

How perchlorate improves excitation-contraction coupling in skeletal muscle fibers.

Published Aug 1, 1983 · H. Lüttgau, G. Gottschalk, L. Kovács

Biophysical journal

Q1 SJR score

61

Citations

4

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

Perchlorate anions enhance contractile force in skeletal muscle fibers by shifting towards more negative membrane potentials, supporting the view that charged particles serve as voltage sensors regulating Ca2+ release from the sarcoplasmic reticulum.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

How perchlorate improves excitation-contraction coupling in skeletal muscle fibers.

Sign up to use Study Snapshot

References

Chaotropic anions and the surface potential of bilayer membranes.

Chaotropic anions perchlorate and thiocyanate alter the surface potential of artificial phospholipid membranes, potentially explaining their effect on erythrocyte membranes.

Citations

Voltage modulates halothane-triggered Ca2+ release in malignant hyperthermia-susceptible muscle

Halothane binding to RyR1 alters the voltage dependence of calcium release in malignant hyperthermia-susceptible muscle fibers, making resting membrane potential a crucial factor for its efficiency in triggering calcium release.

Hans-Christoph Lüttgau 20 July 1926–5 November 2017

Hans-Christoph Lüttgau was a leading muscle physiologist who pioneered work on processes that couple electrical events in muscle with the release of Ca2+ from internal stores, leading to the discovery of the ubiquitous Na-Ca exchanger (NCX) in plasma membranes.

The couplonopathies: A comparative approach to a class of diseases of skeletal and cardiac muscle

Couplonopathies, a new category of striated muscle diseases, reveal structural and functional differences between skeletal and cardiac muscle, which may explain differences in pathogenesis and suggest tissue-specific drug development.

Reciprocal dihydropyridine and ryanodine receptor interactions in skeletal muscle activation

Reciprocal dihydropyridine and ryanodine receptor interactions play a crucial role in skeletal muscle activation, promoting charge transfer and Ca2+ release.

Differential sensitivity to perchlorate and caffeine of tetracaine-resistant Ca2+ release in frog skeletal muscle

Tetracaine blocks a Ca2+ sensitive component of Ca2+ release in frog skeletal muscle, with caffeine restoring the peak and perchlorate potentiating release without affecting charge movement.