Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis.

doi:10.1016/J.BMCL.2003.09.082

Paper

DOI: 10.1016/J.BMCL.2003.09.082

Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis.

Published Jan 5, 2004 · G. Francisco, Zhong Li, J. Albright

Bioorganic & medicinal chemistry letters

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Abstract

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Phenyl thiazolyl urea and carbamate derivatives show promising antibacterial activity against gram-positive and gram-negative bacteria, with 3,4-Difluorophenyl-5-cyanothiazolylurea (3p) showing both gram-positive and gram-

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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2-Phenyl-5,6-dihydro-2H-thieno[3,2-c]pyrazol-3-ol derivatives as new inhibitors of bacterial cell wall biosynthesis.

2-phenyl-5,6-dihydro-2H-thieno[3,2-c]pyrazol-3-ol derivatives show promising inhibitory activity against Staphylococcus aureus and gram-positive bacteria, but show no activity against gram-negative bacteria.

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