Phenylpiperidine selective serotonin reuptake inhibitors interfere with multidrug efflux pump activity in Staphylococcus aureus.

doi:10.1016/S0924-8579(03)00220-6

Paper

Phenylpiperidine selective serotonin reuptake inhibitors interfere with multidrug efflux pump activity in Staphylococcus aureus.

Published Sep 1, 2003 · G. Kaatz, V. Moudgal, S. M. Seo

International journal of antimicrobial agents

Q1 SJR score

84

Citations

1

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Highly Cited

Study Snapshot

Phenylpiperidine selective serotonin reuptake inhibitors (P-SSRIs) can inhibit Staphylococcus aureus multidrug efflux pumps, potentially through physical interaction with NorA.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

Phenylpiperidine selective serotonin reuptake inhibitors interfere with multidrug efflux pump activity in Staphylococcus aureus.

References

Citations

Antimycobacterial, antibiofilm and efflux pump inhibitory activity of extracts from selected Combretum species used in traditional medicine in Zimbabwe

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Droplet Tn‐Seq identifies the primary secretion mechanism for yersiniabactin in Yersinia pestis

Droplet Tn-seq identifies the primary secretion mechanism for yersiniabactin in Yersinia pestis, providing a potential therapeutic target for bacteria using yersiniabactin for metal acquisition.

Antimicrobial activity of antidepressants on normal gut microbiota: Results of the in vitro study

Antidepressants all inhibit the growth of normal gut microorganisms, with mirtazapine showing the greatest activity against L. rhamnosus and C. albicans.

Repurposing Antidepressants and Phenothiazine Antipsychotics as Efflux Pump Inhibitors in Cancer and Infectious Diseases

Antidepressants and phenothiazine antipsychotics show potential as efflux pump inhibitors in treating bacterial infections and cancer, potentially reducing time and costs in drug development.

The potential action of SSRIs in the treatment of skin diseases including atopic dermatitis and slow-healing wounds

SSRIs show potential in treating skin diseases like atopic dermatitis and slow-healing wounds due to their immunomodulatory and antimicrobial properties.