Paper

Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells.

Published Dec 15, 2011 · Sen Li, Y. Lei, Yingjie Jia

Phytomedicine : international journal of phytotherapy and phytopharmacology

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Abstract

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In Vitro StudyHighly Cited

Study Snapshot

Piperine, a piperidine alkaloid from Piper nigrum, can reverse multidrug resistance in cancer cells by multiple mechanisms, making it a promising lead compound for future studies.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells.

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