Paper
New polyhydroxylated pyrrolidines derived from enantiopure 3,6-dihydro-2H-1,2-oxazines.
Published Jun 8, 2002 · R. Pulz, A. Al-Harrasi, H. Reissig
Organic letters
Q1 SJR score
60
Citations
0
Influential Citations
Abstract
[reaction: see text] Diastereoselective hydroborations of enantiopure 3,6-dihydro-2H-1,2-oxazines led to dihydroxy-substituted 1,2-oxazines. Samarium diiodide-induced N-O bond cleavage generated 1,4-amino alcohols which were recyclized to polyhydroxylated pyrrolidines which are potential glycosidase inhibitors.
Study Snapshot
Polyhydroxylated pyrrolidines, derived from enantiopure 3,6-dihydro-2H-1,2-oxazines, show potential as glycosidase inhibitors.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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