Polymer-assisted synthesis of ethyl 2-amino-4,6-diarylpyrimidine-5-carboxylates

doi:10.3998/ARK.5550190.0004.F04

Paper

Polymer-assisted synthesis of ethyl 2-amino-4,6-diarylpyrimidine-5-carboxylates

Published Oct 10, 2003 · J. V. Eynde, Nadège Labuche, Y. Haverbeke

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Abstract

Nine novel ethyl 2-amino-4,6-diarylpyrimidine-5-carboxylates have been synthesized in modest to good yields by a five-step procedure that involves building of the heterocyclic moiety on a solid support derived from Merrifield’s resin and final displacement with an amine.

Study Snapshot

This study demonstrates a five-step procedure for synthesizing novel ethyl 2-amino-4,6-diarylpyrimidine-5-carboxylates using Merrifield's resin and amine displacement, yielding modest to good yields.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Polymer-assisted synthesis of ethyl 2-amino-4,6-diarylpyrimidine-5-carboxylates

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References

Citations

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