Therapeutic Potential of Vicinal Diaryl Azetidin-2-ones

doi:10.1016/B978-0-08-102237-5.00002-X

Paper

Therapeutic Potential of Vicinal Diaryl Azetidin-2-ones

Published 2018 · Rahul B. Ghuge, P. Murumkar

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Abstract

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Study Snapshot

1,4-diaryl azetidin-2-ones show potential as cholesterol absorption inhibitors, antiproliferative, antimicrobial, antitubercular, and anti-inflammatory drugs.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Therapeutic Potential of Vicinal Diaryl Azetidin-2-ones

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References

Citations

Material design and biologically activity of some new azetidines and azetidine-2-ones as antioxident

This research demonstrates promising antioxidant activity of azetidine derivatives and azetidine-2-ones, which can be synthesized and tested in vitro for potential applications in pharmaceuticals.

Biological Evaluation of Azetidine-2-One Derivatives of Ferulic Acid as Promising Anti-Inflammatory Agents

Azetidine-2-one derivatives of ferulic acid show promising anti-inflammatory properties and moderate toxicity, with compound 6b showing the most active effect in a chronic inflammation model.

Monocyclic β-Lactam: A Review on Synthesis and Potential Biological Activities of a Multitarget Core.

Monocyclic -lactams show potential as antibacterial, antitubercular, anticholesterolemic, anticancer, anti-inflammatory, antiviral, and antienzymatic compounds, with potential applications in various fields.