Paper
Pregabalin Is Ineffective for Treating Sciatica Pain
Published Mar 22, 2017 · A. Brett
NEJM Journal Watch
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Abstract
Gabapentin and pregabalin (Lyrica) are prescribed frequently for lumbosacral radicular pain, despite a lack of evidence that they are effective for this condition. In this randomized trial from Australia, researchers randomized 209 patients with sciatica to receive either pregabalin (titrated from 150 mg to 600 mg, depending on response and side effects) or placebo for as …
RCTStudy Snapshot
Pregabalin is ineffective for treating sciatica pain, as evidenced by a randomized trial from Australia.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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