Preparation of bis(2-pyridyl) diselenide derivatives: Synthesis of selenazolo[5,4-b]pyridines and unsymmetrical diorganyl selenides, and evaluation of antioxidant and anticholinesterasic activities

doi:10.1016/J.TETLET.2017.08.030

Paper

Preparation of bis(2-pyridyl) diselenide derivatives: Synthesis of selenazolo[5,4-b]pyridines and unsymmetrical diorganyl selenides, and evaluation of antioxidant and anticholinesterasic activities

Published Sep 20, 2017 · Thiago J Peglow, R. Schumacher, R. Cargnelutti

Tetrahedron Letters

Q3 SJR score

44

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Abstract

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Study Snapshot

Bis(3-amino-2-pyridyl) diselenide is a promising therapeutic agent for Alzheimer's disease and other neurodegenerative disorders due to its antioxidant and inhibitory effects on acetylcholinesterase activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Preparation of bis(2-pyridyl) diselenide derivatives: Synthesis of selenazolo[5,4-b]pyridines and unsymmetrical diorganyl selenides, and evaluation of antioxidant and anticholinesterasic activities

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