Preparation, characterization, in vitro and in vivo studies of olmesartan medoxomil in a ternary solid dispersion with N-methyl-D-glucamine and hydroxypropyl-β-cyclodextrin

doi:10.1016/j.jddst.2020.101546

Paper

Preparation, characterization, in vitro and in vivo studies of olmesartan medoxomil in a ternary solid dispersion with N-methyl-D-glucamine and hydroxypropyl-β-cyclodextrin

Published Apr 1, 2020 · Qihong Zhang, R. Wei, A. Dushkin

Journal of Drug Delivery Science and Technology

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18

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1

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Abstract

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In Vitro Study

Study Snapshot

The synthesized ternary solid dispersion of olmesartan medoxomil with N-methyl-D-glucamine and hydroxypropyl--cyclodextrin improves its oral bioavailability, making it a promising alternative to its pure form for treating hyper

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Preparation, characterization, in vitro and in vivo studies of olmesartan medoxomil in a ternary solid dispersion with N-methyl-D-glucamine and hydroxypropyl-β-cyclodextrin

References

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