(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-[(fluoromethoxy)imino]acetic acid (2), a useful chemical modifier of cephalosporin antibiotics, was efficiently synthesized from 2-[(fluoromethoxy)imino]-1,3-propanedinitrile. The stereochemical structure of 2 was unambiguously determined by X-ray crystallography.

This study efficiently synthesized (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(fluoromethoxy)imino]acetic acid, a useful chemical modifier for cephalosporin antibiotics, with its stereochemical structure determined by

Paper

Efficient preparation of (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(fluoromethoxy)imino]acetic acid

References

Citations