The preparation and oxidation of 3,4-disubstituted 2,5- and 4,5-dihydrothiophenes are described. The oxidation of these dihydrothiophenes with 30% hydrogen peroxide in acetic acid gave the corresponding thiophene derivatives. However, the oxidation of the same compounds with perbenzoic acid in chloroform gave the corresponding sulfone derivatives. The mechanisms for these oxidation are discussed.

Dihydrothiophenes can be prepared and oxidized to produce thiophene and sulfone derivatives, respectively, using hydrogen peroxide in acetic acid and perbenzoic acid in chloroform.

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Preparation and Oxidation of Dihydrothiophenes

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