Profiling of trans-azetidine-2,4-dicarboxylic acid at the human metabotropic glutamate receptors mGlu1b, -2, -4a and -5a.

doi:10.1016/0922-4106(95)90054-3

Paper

Profiling of trans-azetidine-2,4-dicarboxylic acid at the human metabotropic glutamate receptors mGlu1b, -2, -4a and -5a.

Published Feb 15, 1995 · T. Knöpfel, J. Sakaki, P. Flor

European journal of pharmacology

Q1 SJR score

24

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Abstract

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In Vitro Study

Study Snapshot

Trans-azetidine-2,4-dicarboxylic acid is a weak human mGlu 2 receptor agonist, with no significant effects on mGlu 4a receptors and no significant effects on mGlu 1b and mGlu 5a receptors.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Profiling of trans-azetidine-2,4-dicarboxylic acid at the human metabotropic glutamate receptors mGlu1b, -2, -4a and -5a.

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