Paper

Pseudoesters and derivatives. XXIII Reaction of 3-bromo-5-methoxyfuran-2(5H)-one with nucleophiles. Formation of cyclopropane derivatives

Published Jan 1, 1986 · F. Fariña, M. Maestro, M. R. Martín

Tetrahedron

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Abstract

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Study Snapshot

3-bromo-5-methoxyfuran-2(5H)-one reacts with nucleophiles in acetonitrile to form cyclopropane bis-lactones, involving double Michael addition and ring closure via internal nucleophilic substitution of the halogen.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Pseudoesters and derivatives. XXIII Reaction of 3-bromo-5-methoxyfuran-2(5H)-one with nucleophiles. Formation of cyclopropane derivatives

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