The pummerer rearrangement with 7‐(trifluoromethyl)dibenzo[b,e] [1,4]‐thiazepine‐5(11H)‐carboxaldehyde 10‐oxide. Formation of a novel 5,11‐bridged tetracycle

doi:10.1002/JHET.5570150233

Paper

The pummerer rearrangement with 7‐(trifluoromethyl)dibenzo[b,e] [1,4]‐thiazepine‐5(11H)‐carboxaldehyde 10‐oxide. Formation of a novel 5,11‐bridged tetracycle

Published Mar 1, 1978 · H. L. Yale

Journal of Heterocyclic Chemistry

Q3 SJR score

4

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

13-Ethoxy-7-(trifluoromethyl)-11H-11,5-(epoxymethano)dibenzo[b,e][1,4]thiazepine (3) was formed following the Pummerer Rearrangement of 7-(trifluoromethyl)dibenzo[b,e] [1,4]-thiazepine-5(11H)carboxaldehyde 10-oxide (1), when the work-up involved the use of diethyl ether that contained ethanol as a normal ingredient, i.e., the grade of that solvent employed in anesthesia.

Study Snapshot

The Pummerer Rearrangement with 7-(trifluoromethyl)dibenzo[b,e] [1,4]-thiazepine-5(11H)-carboxaldehyde 10-oxide led to the formation of a novel 5,11-bridged te

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

The pummerer rearrangement with 7‐(trifluoromethyl)dibenzo[b,e] [1,4]‐thiazepine‐5(11H)‐carboxaldehyde 10‐oxide. Formation of a novel 5,11‐bridged tetracycle

Sign up to use Study Snapshot

References

Citations

Formation of New 5,11b-Bridged Isoindolo[2,1-b]isoquinolinones Alkaloids through a Tandem Pummerer/π-Cationic Cyclization

Tandem Pummerer/-aromatic cyclization efficiently creates new 5,11b-bridged isoindoloisoquinolinones, offering potential for pharmaceutical applications.

The Pummerer Reaction of Sulfinyl Compounds

The Pummerer reaction is a chemical reaction that forms -functionalized sulfides from sulfoxides, with various analogs and resemblances to other reactions.

Oxidation Adjacent to Sulfur

Oxidation adjacent to a sulfur atom can be used to generate anionic nucleophiles in organic synthesis, but its use in organic synthesis is not covered in this section.