Several 3(2H)-pyridazinones with amino groups at the 5-position of the pyridazine nucleus have been prepared. The 6-aryl-5-halo-3(2H)-pyridazinones obtained from mucochloric and mucobromic acid lead to the corresponding 5-alkylamino-3(2H)-pyridazinones, which were tested as platelet aggregation inhibitors.

6-aryl-5-amino-3(2H)-pyridazinones show potential as platelet aggregation inhibitors, with potential for further development as pharmaceutical agents.

Paper

PYRIDAZINES. XV. SYNTHESIS OF 6-ARYL-5-AMINO-3(2H)-PYRIDAZINONES AS POTENTIAL PLATELET AGGREGATION INHIBITORS

References

Citations