Pyrrole-2-carbohydrazides were synthesized and found to be novel and efficient ligands for the Cu-catalyzed amination of aryl halides with amines in pure water with high yields. A variety of aryl bromides or iodides could be aminated, promoted by the CuI/N′-phenyl-1H-pyrrole-2-carbohydrazide (L13) system, under microwave irradiation or conventional heating without the protection by an inert gas.

Pyrrole-2-carbohydrazides are efficient ligands for the Cu-catalyzed amination of aryl halides with amines in pure water, resulting in high yields and easy amination of various aryl bromides and iod

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Pyrrole‐2‐carbohydrazides as Ligands for Cu‐Catalyzed Amination of Aryl Halides with Amines in Pure Water

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