(R)-(+)-3,5-dinitro-N-(1-phenylethyl)benzothioamide 1 is a potential chiral solvating agent (CSA) for the spectral resolution of enantiomers via 1H NMR spectroscopy. The single enantiomer of 1 was synthesized from commercially available (R)-(+)-a-methylbenzylamine 2 in two steps with 85% yield.

This study synthesized (R)-(+)-3,5-dinitro-N-(1-phenylethyl)benzothioamide 1 from (R)-(+)-a-methylbenzylamine 2 with 85% yield, offering potential for chiral solvating agents

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(R)-(+)-3,5-Dinitro-N-(1-phenylethyl)benzothioamide

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