Radiomodifying action, Pharmacokinetic and Biodistribution of Ethyl 3, 4, 5-trihydroxybenzoate-Implication in development of radiomitigator

doi:10.1038/s41598-019-55316-2

Paper

Radiomodifying action, Pharmacokinetic and Biodistribution of Ethyl 3, 4, 5-trihydroxybenzoate-Implication in development of radiomitigator

Published Dec 1, 2019 · P. Pandey, P. Pandey, B. Ahmed

Scientific Reports

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Rigorous Journal

Study Snapshot

Ethyl 3, 4, 5-trihydroxybenzoate (GAE) shows potential as a radiomodifying agent, inhibiting NF-kB expression and maintaining liver and kidney function after irradiation.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Radiomodifying action, Pharmacokinetic and Biodistribution of Ethyl 3, 4, 5-trihydroxybenzoate-Implication in development of radiomitigator

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References

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Regular radiation safety education significantly increases nurses' compliance with safety procedures, reducing concerns about their well-being and enhancing patient care.

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Radiation countermeasures are needed for acute radiation exposures and related injuries, but no FDA-approved countermeasures exist for acute radiation syndrome.

Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures

Vitamin E analogs, tocopherols and tocotrienols, show potential as radiation countermeasures, potentially acting through free radical quenching or eliciting radioprotective growth factors/cytokines.

Ethyl Gallate Induces Apoptosis of HL-60 Cells by Promoting the Expression of Caspases-8, -9, -3, Apoptosis-Inducing Factor and Endonuclease G

Ethyl gallate induces apoptosis in HL-60 cells through mitochondrial-mediated pathways, suggesting potential therapeutic efficacy in cancer treatment.

Citations

IMMUNOMODULATOR ACTIVITY OF MANGIFERIN FROM MANGO (MANGIFERA INDICA L.) IN CANCER: A SYSTEMATIC REVIEW

Mangiferin from mango shows anticancer activity and immunomodulatory effects, making it a potential candidate drug for anticancer therapy.

The bioactive components as well as the nutritional and health effects of sea buckthorn

Sea buckthorn has a unique mixture of bioactive components, various biological activities, and no toxicological properties, making it a potential treatment for various human diseases.

Hepatorenal Biomacromolecules Modification by Gallic Acid Ethyl Ester in the Gamma-Irradiated Murine Model

Gallic acid ethyl ester can protect liver and kidney cells from ionizing radiation damage by inhibiting cyclooxygenase-2 expression and maintaining oxidative stress parameters.