Triethyl- or triisopropylborane/trifluoromethanesulfonic (triflic) acid is a convenient reagent for the selective reduction of hydroxy substituted carboxylic acids, ketones and aldehydes to yield the corresponding carbonyl compounds. The scope of the reaction, experimental conditions and suggested mechanisms are discussed

Trialkylborane/trifluoromethanesulfonic acid selectively reduces hydroxy carbonyl to carbonyl compounds, offering potential applications in organic synthesis and pharmaceutical research.

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Selective Reduction of Hydroxy Carbonyl to Carbonyl Compounds with Trialkylborane/Trifluoromethanesulfonic Acid

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