Acid-controlled release complexes of podophyllotoxin and etoposide with acyclic cucurbit[n]urils for low cytotoxicity.

doi:10.1016/j.bmc.2018.12.035

Paper

Acid-controlled release complexes of podophyllotoxin and etoposide with acyclic cucurbit[n]urils for low cytotoxicity.

Published Feb 1, 2019 · Fanjie Li, Dan Liu, Xiali Liao

Bioorganic & medicinal chemistry

Q2 SJR score

16

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0

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Abstract

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In Vitro Study

Study Snapshot

Acid-controlled release complexes of podophyllotoxin and etoposide with pH-labile acyclic cucurbit[n]urils maintain good anticancer activity and low cytotoxicity, offering a promising strategy for clinical application.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Acid-controlled release complexes of podophyllotoxin and etoposide with acyclic cucurbit[n]urils for low cytotoxicity.

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