Research on the mode of action of halogen containing thiol alkylating agents on insects. Effect of iodoacetic acid on choline acetylase

doi:10.1016/0022-1910(60)90064-0

Paper

Research on the mode of action of halogen containing thiol alkylating agents on insects. Effect of iodoacetic acid on choline acetylase

Published Mar 1, 1960 · M. Boccacci, G. Natalizi, S. Bettini

Journal of Insect Physiology

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10

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Abstract

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Study Snapshot

Iodoacetic acid does not inhibit choline acetylase activity in the nervous tissue of Musca domestica and Periplaneta americana insects, even at high doses.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Research on the mode of action of halogen containing thiol alkylating agents on insects. Effect of iodoacetic acid on choline acetylase

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References

Determination of acetylcholine in small samples of fresh brain tissue.

This study developed a method for determining "free" acetylcholine in small samples of fresh brain tissue, providing values for normal albino rabbits.

Choline acetylase in the developing nervous system of the rabbit and guinea‐pig

This study aimed to determine the development of choline acetylase in the developing nervous system of rabbits and guinea-pigs, which may serve as a more reliable guide to the development of cholinergic neurones than cholinesterases.

Intracellular Distribution of Choline Acetylase

The intracellular distribution of choline acetylase in rabbit brain is crucial for understanding the chemical transmission of nerve effects.

Mechanisms of acetylcholine synthesis in the blowfly

Choline acetylase and enzymic acetyl donor systems are present in insects, supporting the analogy between cholinesterase inhibitors and lethal effects in mammals.

MITOCHONDRIA IN THE FLIGHT MUSCLES OF INSECTS III. MITOCHONDRIAL CYTOCHROME C IN RELATION TO THE AGING AND WING BEAT FREQUENCY OF FLIES

Aging in Phormia regina blowflies is linked to increased sarcosomal cytochrome c content, which may influence their flight ability.

Choline acetylase specificity in relation to biological function.

Choline acetylase has a strong preference for acetylation of trimethyl aminoethanol, which may impact nerve membrane properties and fatty acid metabolism.

Citations