Research on the Synthesis of 3-chloro-4-methylpyridazine

Paper

Research on the Synthesis of 3-chloro-4-methylpyridazine

Published 2012 · Yang Shao-juan

Guangzhou Chemical Industry

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Abstract

The synthesis method of 3-chloro-4-methylpyridazine was introuced,which was an important intermediate of pesticides and anti-viral drugs.The synthesis was accomplished in four steps,with hydrazine hydrate and citraconic anhydride as the start raw materisls.And its structure was verified by 1HNMR.The total product yield was 30%.This program with mild reaction conditions,realily available materials,and easy operation,was suitable for industrial production.

Study Snapshot

The study introduces a four-step synthesis method for 3-chloro-4-methylpyridazine, an important intermediate in pesticides and anti-viral drugs, with a 30% product yield and mild reaction conditions suitable for industrial production.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Research on the Synthesis of 3-chloro-4-methylpyridazine

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