A Systematic Review of in-vivo Studies on Dietary Mushroom Supplementation for Cognitive Impairment (P14-021-19).

doi:10.1093/cdn/nzz052.P14-021-19

Paper

A Systematic Review of in-vivo Studies on Dietary Mushroom Supplementation for Cognitive Impairment (P14-021-19).

Published Jun 1, 2019 · A. Nkodo

Current developments in nutrition

Q1 SJR score

4

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Objectives A systematic review was undertaken of the evidence on the use of Hericium erinaceus (Reishi), Ganoderma lucidum (Lion's Mane), Ophiocordyceps sinensis (Cordyceps) and Cordyceps militaris (Cordyceps), dietary supplementation on cognitive impairment outcomes. Methods Relevant articles were identified in major databases (PubMed, Embase, Web of Science, and SCOPUS). Key search words were Hericium erinaceus, Ganoderma lucidum, Ophiocordyceps sinensis, Lion's mane, Reishi, Cordyceps, cognitive, memory, dementia, Alzheimer's. Included studies were peer-reviewed in-vivo articles published in English before January 2019, with cognitive outcomes. Results Twenty-five (25) of 194 studies met the inclusion criteria: eight (8) studies on lion's mane mushroom, seven (7) studies on reishi mushroom and ten (10) studies on cordyceps mushroom. Three (3) randomized-controlled trials were included in this review. Studies varied by animals used, preparation of supplement, dosage and duration of supplementation, and cognitive outcomes. Twenty-two (22) animal studies found positive results (P < 0.05) on at least one of the doses tested for at least one cognitive impairment outcome. Of the human trials, two (2) studies found positive results (P < 0.05) on at least one of the cognitive assessments. Conclusions Despite heterogeneous study design, the results of this review suggest that dietary supplementation with lion's mane, reishi and cordyceps mushrooms may have a beneficial effect on cognitive impairment. Further clinical research studies are needed to demonstrate the potential medicinal benefits of dietary mushroom supplementation in humans with cognitive impairments. Funding Sources No external funding.

Systematic Review

Very Rigorous Journal

Study Snapshot

Dietary supplementation with lion's mane, reishi, and cordyceps mushrooms may have a beneficial effect on cognitive impairment.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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A Systematic Review of in-vivo Studies on Dietary Mushroom Supplementation for Cognitive Impairment (P14-021-19).

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References

Citations

Lion’s Mane Mushroom- From Culinary to Medicine

Lion's Mane mushroom offers potential health benefits, including brain health, mood stabilization, and cancer prevention, but should be used as a complementary dietary addition rather than a substitute for medical treatments.

Filamentous fungi for future functional food and feed.

Mushrooms and mycelia are increasingly used in food and feed due to their high nutritional value, lipids, vitamins, fiber, and taste, as well as their potential for improving livestock health and gut health.

Examining the health effects and bioactive components in Agaricus bisporus mushrooms: a scoping review.

Consumption of Agaricus bisporus mushrooms improves vitamin D status, metabolic syndrome, immune function, gastrointestinal health, and cancer, with variations in concentrations depending on cooking method and UVB exposure.

Environmental factors in the development of Alzheimer’s disease

Clinical decision-making is a complex process influenced by competence, confidence, organizational support, and the clinical environment, requiring a nuanced understanding for patient-centered care and improved healthcare outcomes.