The role of oxidative stress in DNA damage in pancreatic β cells induced by di-(2-ethylhexyl) phthalate.

doi:10.1016/j.cbi.2017.01.015

Paper

The role of oxidative stress in DNA damage in pancreatic β cells induced by di-(2-ethylhexyl) phthalate.

Published Mar 1, 2017 · Yan She, Liping Jiang, Liangliang Zheng

Chemico-biological interactions

Q1 SJR score

48

Citations

2

Influential Citations

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Abstract

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In Vitro Study

Study Snapshot

DEHP exposure impairs pancreatic beta cell function through oxidative stress and p53 and ATM activation, leading to Insulin Resistance and type 2 diabetes.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

The role of oxidative stress in DNA damage in pancreatic β cells induced by di-(2-ethylhexyl) phthalate.

References

Citations