Ru-catalyzed enantioselective preparation of methyl (R)-o-chloromandelate and its application in the synthesis of (S)-Clopidogrel

doi:10.1016/J.JORGANCHEM.2009.02.008

Paper

Ru-catalyzed enantioselective preparation of methyl (R)-o-chloromandelate and its application in the synthesis of (S)-Clopidogrel

Published Jun 1, 2009 · Lu Yin, Wenjun Shan, X. Jia

Journal of Organometallic Chemistry

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33

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Abstract

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Study Snapshot

Ru-catalyzed enantioselective preparation of methyl (R)-o-chloromandelate enables the synthesis of (S)-Clopidogrel with up to 92% ee.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Ru-catalyzed enantioselective preparation of methyl (R)-o-chloromandelate and its application in the synthesis of (S)-Clopidogrel

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