A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with dual antiemetic and gastroprokinetic activities.

doi:10.1016/S0960-894X(98)00341-2

Paper

DOI: 10.1016/S0960-894X(98)00341-2

A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with dual antiemetic and gastroprokinetic activities.

Published 1998 · Y Hirokawa, H Yamazaki, N Yoshida

Bioorganic & medicinal chemistry letters

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

These novel 6-methoxy-1H-benzotriazole-5-carboxamide derivatives show potent antiemetic and gastroprokinetic activities, offering potential therapeutic applications in treating nausea and vomiting.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Citations

DOI: 10.3390/ecmc2019-06284

Design, synthesis, anti-HIV and antimicrobial study of some 3-(1H-benzo[d][1,2,3]triazol-1-yl)-N-phenylalkylamide derivatives

Compounds 7h, 7j, 8i, and 8j show high antibacterial and antifungal activity, with potential as a broad-spectrum HIV treatment.

2019·0citations·Rohit Singh·Proceedings of 5th International Electronic Conference on Medicinal Chemistry

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DA-9701 (Motilitone): A Multi-Targeting Botanical Drug for the Treatment of Functional Dyspepsia

DA-9701 (Motilitone) is a promising alternative treatment for functional dyspepsia, improving symptoms and gastrointestinal functions while showing better safety compared to conventional medicines.

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Benzotriazole: An overview on its versatile biological behavior

Benzotriazole derivatives show diverse biological properties and potential as antimicrobial, antiparasitic, and antitumor agents, with less adverse effects than their parent benzimidazole.

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DA-9701: A New Multi-Acting Drug for the Treatment of Functional Dyspepsia

DA-9701 is a new, multi-action herbal drug that effectively treats functional dyspepsia by promoting fundus relaxation, visceral analgesia, and prokinetic effects, with a safer profile compared to other treatments.

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A new polymorph of 2-(2H-benzotriazol-2-yl)acetic acid

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