A new ionic liquid, 3-hydroxypropanaminium acetate (HPAA) [H3N+-CH2-CH2-CH2-OH][CH3COO−], was synthesized for the first time and used as an efficient and recoverable catalyst in the synthesis of 2-amino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives by condensing together 4-hydroxycoumarin, aldehydes and malononitrile at room temperature. The catalyst can be reused for four times without noticeable loss of activity.

The new ionic liquid 3-hydroxypropanaminium acetate (HPAA) efficiently catalyzes the synthesis of 2-amino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives, with a Green approach

Journal of the Iranian Chemical Society

A simple Green approach to the synthesis of 2-amino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives catalyzed by 3-hydroxypropanaminium acetate (HPAA) as a new ionic liquid

Paper

A simple Green approach to the synthesis of 2-amino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives catalyzed by 3-hydroxypropanaminium acetate (HPAA) as a new ionic liquid

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