Sinigrin inhibits production of inflammatory mediators by suppressing NF‐&kgr;B/MAPK pathways or NLRP3 inflammasome activation in macrophages

doi:10.1016/j.intimp.2017.01.032

Paper

Sinigrin inhibits production of inflammatory mediators by suppressing NF‐&kgr;B/MAPK pathways or NLRP3 inflammasome activation in macrophages

Published Apr 1, 2017 · Heeweon Lee, C. Lee, D. Rhee

International Immunopharmacology

Q1 SJR score

51

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1

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Abstract

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In Vitro Study

Rigorous Journal

Study Snapshot

Sinigrin, found in broccoli, brussels sprouts, and black mustard seeds, suppresses inflammatory mediator production by inhibiting NF-B/MAPK pathways or NLRP3 inflammasome activation in macrophages.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sinigrin inhibits production of inflammatory mediators by suppressing NF‐&kgr;B/MAPK pathways or NLRP3 inflammasome activation in macrophages

References

Citations