Paper

The solubilization of the poorly water soluble drug nifedipine by water soluble 4-sulphonic calix[n]arenes.

Published Nov 1, 2004 · Wenzhan Yang, M. D. de Villiers

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

102

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Abstract

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Study Snapshot

4-sulphonic calix[n]arenes significantly improve the solubility of the poorly water soluble drug nifedipine, with 4-sulphonic calix[8]arene showing the most significant improvement.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

The solubilization of the poorly water soluble drug nifedipine by water soluble 4-sulphonic calix[n]arenes.

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