In the current study, a compound 5-phenyl-1,3,4 -oxadiazole-2-thiol was synthesized by converting variously benzoic acids successively into the corresponding esters, hydrazides. The structure of the synthesized compound was confirmed based on 1H-NMR, IR, UV-Vis and mass spectral data. The synthesized compounds were screened for antimicrobial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus and fungus Candida albican, Aspergillusniger and Candida krusei.

5-Phenyl-1,3,4-oxadiazole-2-thiol shows promising antimicrobial activity against bacteria and fungi, with potential applications in pharmaceuticals and cosmetics.

Paper

Spectral and Biological Investigation of 5-Phenyl-1,3,4-Oxadiazole-2-Thiol

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