Paper

Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides.

Published Dec 28, 2015 · R. Christie, R. Fleming, Binyam Z Bezabeh

Journal of controlled release : official journal of the Controlled Release Society

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro StudyHighly Cited

Study Snapshot

N-aryl maleimides effectively stabilize cysteine-linked antibody-drug conjugates, maintaining high conjugation efficiency and reducing deconjugation in the bloodstream.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides.

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