The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone.

doi:10.1016/j.bmcl.2010.09.113

Paper

The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone.

Published Nov 15, 2010 · Yuxiang Dong, K. J. Mccullough, S. Wittlin

Bioorganic & medicinal chemistry letters

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32

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Abstract

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In Vitro Study

Study Snapshot

Dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone show diverse structures and antimalarial activity, with polarity increasing reducing their potency against Plasmodium falciparum.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone.

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