Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.

doi:10.1016/j.ejmech.2021.113253

Paper

Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.

Published Feb 4, 2021 · William Nguyen, Madeline G. Dans, A. Ngo

European journal of medicinal chemistry

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12

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Abstract

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Study Snapshot

Phenylsulfonyl piperazines show potential as new antimalarials by blocking erythrocytic invasion, offering potential as tools for studying Plasmodium erythrocyte invasion.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.

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