Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines.

doi:10.1016/j.ejmech.2009.11.006

Paper

Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines.

Published Feb 1, 2010 · Sébastien Madonna, C. Beclin, Y. Laras

European journal of medicinal chemistry

Q2 SJR score

40

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

Bis 8-hydroxyquinoline substituted benzylamines show promising anti-cancer activity by targeting accessible thiols from specific proteins and inducing potent anti-cancer effects in glioma and carcinoma models.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines.

References

Citations