Paper

Structure-activity studies leading to potent chloride channel blockers: 5e-tert-Butyl-2-[4-(substituted-ethynyl)phenyl]-1,3-dithianes.

Published Dec 1, 1994 · Q. X. Li, J. Casida

Bioorganic & medicinal chemistry

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Abstract

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Study Snapshot

5e-tert-Butyl-2-[4-(substituted-ethynyl)phenyl]-1,3-dithianes with selected functional groups are potent chloride channel blockers, with the R substituent's high activity being due to its polari

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Structure-activity studies leading to potent chloride channel blockers: 5e-tert-Butyl-2-[4-(substituted-ethynyl)phenyl]-1,3-dithianes.

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