Structure-property relationship of 3-(4-substituted benzyl)-1,3-diazaspiro[4.4]nonane-2,4-diones as new potentional anticonvulsant agents. An experimental and theoretical study

doi:10.1016/J.MOLSTRUC.2016.07.069

Paper

Structure-property relationship of 3-(4-substituted benzyl)-1,3-diazaspiro[4.4]nonane-2,4-diones as new potentional anticonvulsant agents. An experimental and theoretical study

Published Jan 5, 2017 · A. Lazic, B. Božić, V. Vitnik

Journal of Molecular Structure

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7

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Abstract

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Study Snapshot

Newly synthesized 3-(4-substituted benzyl)-1,3-diazaspiro[4.4]nonane-2,4-diones show potential as new anticonvulsant agents with lipophilicities comparable to Phenytoin.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Structure-property relationship of 3-(4-substituted benzyl)-1,3-diazaspiro[4.4]nonane-2,4-diones as new potentional anticonvulsant agents. An experimental and theoretical study

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