Studies on 1,3‐indandione: Synthesis of Fluorenones and Indeno(2,1‐c)pyridazine

doi:10.1002/PRAC.19903320508

Paper

Studies on 1,3‐indandione: Synthesis of Fluorenones and Indeno(2,1‐c)pyridazine

Published 1990 · M. Sofan, F. El‐Taweel, A. Elagamey

Journal Fur Praktische Chemie-chemiker-zeitung

UNKNOWN SJR score

7

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0

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Abstract

1,1-Dicyanomethylene-3-indanone (2) reacted with cinnamonitriles 1a-c to afford fluorenone derivatives 6a-c. Compounds 6a-c were also obtained when treating 2 with 1d-f. The coupling of 2 with aromatic diazonium chlorides resulted in the formation of the hydrazones 8a-c. 8a readily cyclized to indeno[2,1-c]pyridazine (9a) in acidic medium. The action of 1d-f on enaminone 3 was also studied.

Study Snapshot

1,3-indandione can be used to synthesize fluorenone derivatives and indeno[2,1-c]pyridazine, with potential applications in organic synthesis and drug discovery.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Studies on 1,3‐indandione: Synthesis of Fluorenones and Indeno(2,1‐c)pyridazine

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References

α,β-Unsaturated nitriles in heterocyclic synthesis: Synthesis of some new pyrazolo[1,5-a]pyrimidine derivatives

This study demonstrates the potential of -unsaturated nitriles in heterocyclic synthesis, leading to the synthesis of new pyrazolo[1,5-a]pyrimidine derivatives9,11, and12.

Citations

A highly efficient one-pot synthesis of indenopyridine-fused spirocyclic systems

This study presents an efficient, eco-friendly method for synthesizing diverse spirooxindoles with medicinally valuable indenopyridine moieties using a one-pot, metal-free process.

Synthesis of some new indeno(1,2-e)pyrazolo(5,1-c)-1,2,4-triazin-6-one and indeno(2,1-c)pyridazine-4-carbonitrile derivatives

New indeno(1,2-e)pyrazolo(5,1-c)-1,2,4-triazin-6-one and indeno(2,1-c)pyridazine-4-carbonitrile derivatives were synthesized using various chemical and spectral methods.

3-(phenylhydrazono)-indan-1-one and 2-dimethylaminomethylene-3-(phenylhydrazono)-indan-1-one as useful synthons for the construction of new heterocyclic systems

The synthons 3-(phenylhydrazono)-indan-1-one and 2-dimethylaminomethylene-3-(phenylhydrazono)-indan-1-one can be used to construct new heterocyclic systems, yielding indenopyrazole derivatives, indeno