Comparative studies of the antineoplastic activity of 5-hydroxy-2-formylpyridine thiosemicarbazone and its seleno-semicarbazone, guanylhydrazone and semicarbazone analogs.

doi:10.1016/0006-2952(74)90233-0

Paper

Comparative studies of the antineoplastic activity of 5-hydroxy-2-formylpyridine thiosemicarbazone and its seleno-semicarbazone, guanylhydrazone and semicarbazone analogs.

Published Sep 1, 1974 · Krishna C. Agrawal, Krishna C. Agrawal, Barbara A. Booth

Biochemical pharmacology

Q1 SJR score

36

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1

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Abstract

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In Vitro Study

Study Snapshot

5-HP is the most active antineoplastic agent, with its potency correlated to its ability to inhibit DNA synthesis and metal binding capacity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Comparative studies of the antineoplastic activity of 5-hydroxy-2-formylpyridine thiosemicarbazone and its seleno-semicarbazone, guanylhydrazone and semicarbazone analogs.

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