Studies on the reactivity of acyl glucuronides--VII. Salicyl acyl glucuronide reactivity in vitro and covalent binding of salicylic acid to plasma protein of humans taking aspirin.

doi:10.1016/0006-2952(94)90177-5

Paper

DOI: 10.1016/0006-2952(94)90177-5

Studies on the reactivity of acyl glucuronides--VII. Salicyl acyl glucuronide reactivity in vitro and covalent binding of salicylic acid to plasma protein of humans taking aspirin.

Published Feb 9, 1994 · R. Dickinson, P. Baker, A. R. King

Biochemical pharmacology

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

Salicyl acyl glucuronide (SAG) reactivity allows for covalent attachment of the salicylic acid moiety of aspirin to tissue macromolecules, in addition to its well-known acetylating capacity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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