Paper
An NMR Study of Halogenated 1,4‐Dihydro‐1‐ethyl‐4‐oxoquinoline‐3‐carboxylates
Published Nov 1, 1996 · B. Podányi, G. Kereszturi, L. Vasvári‐Debreczy
Magnetic Resonance in Chemistry
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5
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Abstract
Ethyl 1,4‐dihydro‐1‐ethyl‐4‐oxoquinoline‐3‐carboxylate and 29 of its mono‐, di‐ and tri‐fluoro and/or ‐chloro derivatives were synthesized and their 1H, 13C and 19F NMR spectra were recorded. 1H, 13C and 19F chemical shifts, JHH, JFH, JCF and JFF coupling constants are reported. The 13C substituent chemical shift values of the chloro and fluoro substituents were calculated by linear multiple regression.
Study Snapshot
Halogenated 1,4-dihydro-1,4-ethyl-4-oxoquinoline-3-carboxylates show promising potential for pharmaceutical applications due to their unique chemical shifts and pharmacological properties.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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