Study on the New Synthesis Process of 2-(4-Aminophenyl) Ethanol

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Study on the New Synthesis Process of 2-(4-Aminophenyl) Ethanol

Published 2013 · Zhang Wei-xing

Chemistry World

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Abstract

The new synthesis process for 2-(4-aminophenyl) ethanol,a key intermediate of cardiovascular drugs,was studied using β-phenylethanol as raw material.Through four step reactions such as esterification,nitrification,hydrolysis,and reduction,the total yield of 2-(4-aminophenyl) ethanol reached 66.4%,and the HPLC purity was 99.77%.The product structure was identified with melting point and GC-MS.The new technology has great industrialized application value.

Study Snapshot

The new synthesis process for 2-(4-aminophenyl) ethanol, a key intermediate in cardiovascular drugs, achieves 66.4% total yield and 99.77% HPLC purity, with potential industrial applications.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Study on the New Synthesis Process of 2-(4-Aminophenyl) Ethanol

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