Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines.

doi:10.1016/j.ejmech.2013.08.009

Paper

Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines.

Published Oct 1, 2013 · A. Imramovský, Radek Jorda, K. Pauk

European journal of medicinal chemistry

Q2 SJR score

26

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

Substituted 2-hydroxy-N-(arylalkyl)benzamides show potent antiproliferative and cytotoxic activity against various cancer cell lines, with one compound showing dose-dependent apoptosis in melanoma cell line G361.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines.

Sign up to use Study Snapshot

References

Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase β.

Novel somatostatin peptide analogues, specifically compound 4, effectively inhibit human cancer cell growth and DNA repair, with potential synergistic effects with methyl methane sulfonate.

Polymers from amino acids: development of dual ester-urethane melt condensation approach and mechanistic aspects.

The new dual ester-urethane melt condensation method creates environmentally friendly, renewable thermoplastics from natural amino acids, offering potential for industrial applications.

Combinatorial drug therapy for cancer in the post-genomic era

Combinatorial targeted therapy, combining multiple targeted drugs, could overcome polygenic cancer drug resistance and improve personalized cancer medicine strategies.

p53/HMGB1 complexes regulate autophagy and apoptosis.

The HMGB1/p53 complex plays a crucial role in regulating tumor cell death and survival, with HMGB1 promoting autophagy and p53 regulating apoptosis in carcinogenesis.

Novel Insights into the Interplay between Apoptosis and Autophagy

Autophagy plays a complex role in cancer cell survival and growth, with its regulation affecting both survival and growth responses to various stresses.

Citations