Furo[3,2-c] pyridine (I) was nitrated to give 2-nitrofuro[3,2-c]pyridine (II). Bromination and chlorination of I gave, respectively, 2,3-dibromo-2,3-dihydrofuro[3,2-c]pyridine (III) and 2,3-dichloro-2,3-dihydrofuro[3,2-c]pyridine (IV). Oxidation of I with hydrogen peroxide afforded furo[3,2-c]pyridine 5-oxide (V) which was converted to I by phosphorus trichloride and to 4-chlorofuro[3,2-c]pyridine (VI) by phosphorus oxychloride.

Electrophilic substitution of furo[3,2-c] pyridine leads to various products, including 2,3-dibromo-2,3-dihydrofuro[3,2-c]pyridine, 2,3-dichloro-2,3-dihydrofuro[3,2-c]pyr

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Electrophilic substitution of furo[3,2‐c] pyridine

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