Paper

The successive substitution of halogens in 4-chloro-6-iodoquinoline by aryl groups in cross-coupling reactions with arylboronic acids

Published Sep 30, 2002 · A. V. Tsvetkov, G. Latyshev, N. Lukashev

Tetrahedron Letters

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Abstract

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Study Snapshot

Selective stepwise substitution of iodine and chlorine atoms in 4-chloro-6-iodoquinoline allows for the synthesis of diarylquinolines with different aryl groups in 4- and 6-positions, in a one-pot procedure with high yields.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

The successive substitution of halogens in 4-chloro-6-iodoquinoline by aryl groups in cross-coupling reactions with arylboronic acids

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