Paper

Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells.

Published Sep 2, 2005 · Young-Chul Park, Jin Hee Jeong, Ki-Jae Park

Life sciences

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Abstract

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In Vitro Study

Study Snapshot

Sulindac induces large-scale DNA fragmentation without oligonucleosomal DNA fragmentation in HT-29 colon cancer cells, suggesting a predominantly AIF-mediated cell death process.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells.

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